TEN ZERO PDRN Collagen Hidden Shot 30ml — skin repair booster
TEN ZERO PDRN Collagen Hidden Shot 30ml — skin repair booster
The ingredient dermatologists use — now in a serum
PDRN — Polydeoxyribonucleotide — started in clinical medicine. It's derived from salmon DNA fragments and has been used in Korean and Italian aesthetic medicine for over 20 years to accelerate wound healing, reduce inflammation, and stimulate collagen synthesis in post-procedure skin. What was once only available via in-clinic injection is now formulated into a topical serum — TEN ZERO's PDRN Hidden Shot delivers 2,500ppm of this repair-activating compound in a daily-use format.
How PDRN works
PDRN acts on A2A adenosine receptors in the skin — the same receptors that regulate tissue repair signalling. When these receptors are activated, the skin responds by upregulating growth factors (VEGF, TGF-β) that drive collagen production and accelerate cell regeneration. Clinical studies using injectable PDRN have demonstrated measurable improvements in skin thickness, elasticity, and wound closure rates. Topical PDRN delivers these signals at lower intensity without needles — making it suitable for daily maintenance between clinic visits or as a standalone repair protocol.
Key actives
| Ingredient | Role |
|---|---|
| PDRN (Polydeoxyribonucleotide) 2,500ppm | Adenosine receptor activation; collagen synthesis stimulation; tissue repair |
| Hydrolysed collagen | Surface moisture binding; skin plumping; supports dermis elasticity |
| Adenosine | KFDA-certified anti-wrinkle active; synergistic with PDRN pathway |
| Niacinamide | Barrier strengthening; tone evening; reduces post-inflammatory redness |
| Hyaluronic acid | Draws and holds moisture at multiple skin depths |
| Panthenol (B5) | Soothes and supports barrier repair |
How to use
- Apply after cleansing and toning — to slightly damp skin for enhanced absorption
- Dispense 3–4 drops and press gently into face and neck
- Allow 60 seconds before applying moisturiser
- Use morning and evening; follow with SPF 50+ in the morning
- Works well as a booster layered under your existing serum or moisturiser
Who this is for
- Anyone who wants clinic-grade repair ingredients in a daily at-home routine
- Skin recovering from laser, chemical peel, microneedling, or other professional treatments
- Mature skin looking to support natural collagen production as it declines with age
- Sensitive skin prone to inflammation — PDRN is notably anti-inflammatory
Specs
| Volume | 30 ml |
| PDRN concentration | 2,500 ppm |
| Skin type | All — especially post-procedure, mature, or sensitive skin |
| Brand | TEN ZERO (텐제로) |
| Country of origin | South Korea |
Shipping & delivery
Ships from South Korea via express international courier. Estimated delivery: 7–12 business days to Australia. Tracking provided within 2 business days of dispatch. Arrives in protective packaging — safe for air transport.
Frequently asked questions
What is salmon DNA doing in a skincare product?
PDRN is derived from salmon sperm DNA through a controlled extraction and purification process. The resulting molecule is a short DNA fragment (polydeoxynucleotide) — not an intact DNA strand. It does not interact with human DNA; instead, it binds to surface receptors on skin cells that govern repair and regeneration. The salmon origin is simply because salmon DNA fragments are highly biocompatible with human receptor systems — a fact established in decades of clinical wound-care research.
Is topical PDRN as effective as injectable PDRN?
Injectable PDRN delivers higher concentrations directly to the dermis. Topical PDRN penetrates the skin barrier at lower effective concentrations, making the effect gentler and more gradual — but meaningful with consistent use. Think of it as maintenance between clinic treatments, or as a daily repair protocol for those not pursuing injectable aesthetics. The anti-inflammatory and receptor-activation effects are observable in topical application at concentrations above 2,000ppm.
Can I use this right after a skin treatment (laser, peel, microneedling)?
Yes — PDRN is actually one of the most clinician-recommended post-procedure ingredients because of its wound-healing and anti-inflammatory properties. After microneedling, the temporary microchannels in skin also allow significantly deeper penetration of topical PDRN than regular intact skin provides. Wait until the skin is no longer raw or open — typically 24–48 hours post-procedure — then begin applying.
How does this compare to growth factor serums?
Growth factor serums (EGF, FGF, IGF) stimulate cell proliferation directly. PDRN works upstream — it activates the receptor that tells cells to enter repair mode, which then triggers growth factor release internally. They can be used together (PDRN creates the signalling environment; growth factors amplify it), or PDRN alone is sufficient for a solid daily repair baseline.